Unveiling rare hemorragic complications of enoxaparin therapy. A clinical review

Abdalani B., Moufid O., Abdellah B. et al.

ABSTRACT

Background. Enoxaparin sodium, a low molecular weight heparin, is widely used for prophylaxis and treatment of thrombotic diseases. Despite its efficacy, enoxaparin can lead to complications, including hemorrhagic events.

Case presentation. We present a case of a 58-year-old man with ischemic heart disease and heart failure who developed a rare hemorrhagic complication—an extensive thigh muscle hematoma—while on enoxaparin therapy. The patient was managed conservatively with blood transfusion and discontinuation of anticoagulation, resulting in favorable outcomes.

Conclusions. This case underscores the importance of understanding the risks associated with enoxaparin therapy and highlights the need for individualized patient management strategies. Furthermore, it emphasizes the significance of interdisciplinary collaboration in addressing rare complications to optimize patient care. Further research is warranted to enhance our understanding and management of such complications in thromboembolic disorders.

Key words: Enoxaparin, soft muscles hematoma, complications, management.

For citation:

Abdalani B., Mufid O., Abdellah B. et al. Disclosure of rare hemorrhagic complications of enoxaparin therapy. A clinical case. International Journal of Cardiovascular Diseases. 2025. 13(45):43-50 DOI: 10.24412/ 2311-1623-2025-45-53-61